This advanced course examines the complete ASIC chips signal system of the Antminer T21 BHB68701 hash board. Understand the five critical signals (RST, CI, RI, CLK, BI) transmission through 108 BM1368PB chips, including level shifter chips U1 and U2 that convert between control board 3.3V and ASIC 1.2V logic. Learn the operational differences between intra-domain signaling and cross-domain communication enhanced by 11 operational amplifier modules. Comprehensive measurement procedures cover signal voltages at various test points (1.2V for RST/CI/RI, 0.6V for CLK), amplifier power supply verification, and level shifter chip analysis. Essential for diagnosing communication failures in Bitmain T21 hardware repair scenarios.